磷脂酰肌醇 PI4P

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产品详细说明

Cat. Number	H1919-1
Chemical Name	Phosphatidylinositol 4-phosphate, dipalmitoyl, (NH4+salt) (DPPI-4-P)
Category	synthetic
Mol. Formula	C₄₁H₇₇O₁₆P₂•3NH₄
Mol. Weight	942
Qty 1	1mg
Appearance	solid
Application Notes	98+% 1H NMR, 31P NMR
Synonym	DPPI-4-P; PI-4-P dipalmitoyl,(NH4+salt)
Solubility	methanol, chloroform/methanol/DI water, 4:3:1; slightly soluble in water
Storage condition	-20°C
References	1. J. Zhang et al. “Role of Type I Phosphatidylinositol-4-Phosphate 5-Kinase in Insulin Secretion, Glucose metabolism, and Membrane Potential in INS-1 -Cells” Endocrinology, Vol.150(5) pp. 2127-2135, 2008 2. P.W. Majerus, “Inositol phosphate biochemistry” Annual Review of Biochemistry Vol. 61 pp. 225-250, 1992 3. Ao-Lin Hsu, et al. “Novel Function of Phosphoinositide 3-Kinase in T Cell Ca2+ Signaling: A Phosphatidylinositol 3,4,5-Trisphostphate-Mediated Ca2+ Entry Mechanism” Journal of Biological Chemistry May, Vol. 275 pp. 16242-16250, 2000 4. H. Shimamura, et al. “The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad” Journal of American Society of Nephrology Vol. 14 pp. 1427-1434, 2003