2020年4月27日,据欧盟食品安全局(EFSA)消息,应欧盟委员会的要求,欧盟动物饲料添加剂和产品(FEEDAP)研究小组就转基因谷氨酸棒杆菌(Corynebacterium glutamicum)DSM 32932发酵生产的L-赖氨酸盐酸盐(L-Lysine Monohydrochloride)作为所有动物物种添加剂的安全性和有效性发表科学意见。
经过评估,专家小组认为该添加剂对目标物种、消费者和环境都是安全的,是非反刍动物赖氨酸的有效来源。部分原文报道如下:
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l‐lysine monohydrochloride produced by fermentation with the genetically modified strain of Corynebacterium glutamicum DSM 32932. Neither the production strain nor its recombinant DNA were detected in the final product. The additive does not pose any safety concern associated with the genetic modification of the production strain. l‐Lysine HCl produced by C. glutamicum DSM 32932 is considered safe for the target species, for the consumer and for the environment. l‐Lysine HCl produced by C. glutamicum DSM 32932 is not toxic by inhalation; it is not irritant to skin and not a skin sensitiser. The additive is not corrosive to eyes but it should be considered as an eye irritant. In general, l‐lysine HCl is considered as an efficacious source of the essential amino acid l‐lysine for non‐ruminant animal species. For the supplemental l‐lysine to be as efficacious in ruminants as in non‐ruminant species, it would require protection against degradation in the rumen.